In the 1980s, the young Guo Xueping entered Shandong University and studied biochemical pharmacy under Zhang Tianmin. Professor Zhang Tianmin is a pioneer in biochemical drug research in my country and is known as the "father of hyaluronic acid in China". Guo Xueping followed Zhang Tianmin to study hyaluronic acid (also known as hyaluronic acid), a substance owned by the human body, is widely present in tissues such as the skin, eyes, joints, and umbilical cord, and is closely related to health. Soon, Guo Xueping also mastered the extraction method. However, in China, large amounts of cockscombs are consumed as food ingredient, and the cost and raw material acquisition restrict the industrial transformation of the extraction method in China. By chance, he learned that some people abroad tried to produce hyaluronic acid through microbial fermentation. It would be a revolutionary change if hyaluronic acid could be obtained through fermentation. One day two years later, he walked into the laboratory as usual and poured the fermentation broth into the alcohol, and hyaluronic acid poured out like a cotton ball. He knew he had succeeded, and the moments of excitement became moments of history.

It was also at this time that Zhao Yan accidentally met Guo Xueping with her business dream. Guo Xueping, who holds the core technology of microbial fermentation, meets Zhao Yan, who has a keen sense of business and majors in biology in college. The future of hyaluronic acid is depicted at that moment, and Huaxi Bio's potential is gradually stimulated. After taking over Huaxi Biologics, hyaluronic acid, as a body's own substance, has its safe and natural moisturizing effects, attracted Zhao Yan's attention. At that time, hyaluronic acid had begun to be applied in many fields internationally, and Guo Xueping and his R&D team were also conducting research on the transformation of hyaluronic acid from raw materials to terminals. Zhao Yan's keen sense of business and creativity once again combines with Guo Xueping's persistence in scientific exploration.

In 2012, "Runbaiyan Modified Hyaluronate Sodium Hyaluronate Gel for Injection" was approved by the former State Food and Drug Administration (CFDA). This is a domestically approved domestic crosslinked hyaluronate soft tissue filler, breaking the foreign country. The market monopoly of brands. From substances to products, from laboratories to industrialization, hyaluronic acid has begun to play its role. From nourishing Zhao Yan himself to "moistening the world's face", hyaluronic acid has changed from a rare substance to a terminal product that benefits the public. "Runbaiyan" has begun to enter the lives of consumers. In 2014, BFS sterile filling technology used for eye drop production was used in the production of functional skin care products. Runbaiyan launched the "Honey Hyaluronic Acid Hydrochloric Acid" product, creating a new category of hyaluronic Acid "Sub-spreading Liquid" .

As Runbaiyan is loved by more and more consumers, Zhao Yan realized that Runbaiyan's product power can already compete with international brands. She began to think about how to let "China Intelligent Manufacturing" go to the world. Zhao Yan, who loves culture and art, thought of the Forbidden City, the master of Chinese civilization. In 2018, the "Runbaiyan·Forbidden City Lipstick" jointly launched by Huaxi Biology and the Palace Museum became a hit and became world-renowned. Guo Xueping and his team used the company's patented ingredient Hyaluronic acid as dispersed hyaluronic acid in lipsticks, solving the recognized problem in the cosmetics industry - highly hydrophilic hyaluronic acid is difficult to add to the products of full oil formula, allowing hyaluronic acid to break through "Cosmetics" restricted area".

To date, all the core products of Runbaiyan are based on hyaluronic acid as the core raw material, and through biological skin revitalization technology, they work together with many biological active substances. Based on Huaxi Bio's unique patented enzyme cutting technology for hyaluronic acid production, Runbaiyan has unique advantages in the complexing of hyaluronic acid with different molecular weights, and can truly exert the efficacy of hyaluronic acid at all levels of the skin. The parent company Huaxi Bio has successively participated in the formulation of four national industry standards related to hyaluronic acid, participated in the revision of the hyaluronic acid standards in the European Pharmacopoeia and the Chinese Pharmacopoeia, and submitted the hyaluronic acid monograph on the United States Pharmacopoeia.

Now, Runbaiyan has gathered the R&D team and technical achievements that are currently at the forefront of the hyaluronic acid field. In the future, it will continue to inherit the technological genes of the parent brand Huaxi Biology, bring more high-quality products to consumers, and use technological wisdom to run the world. The face of the word.