Esco has been established in Singapore since 1978 and has become the pioneer of clean room technology in Southeast Asia. Esco was founded to provide high-tech solutions for clean air in high-tech and life sciences industries. From the beginning, Esco has gained a reputation for innovative research and development in the laboratory and clean room industries around the world.

The Singapore headquarters introduces product research, R&D, manufacturing and customer service. In eight offices around the world, Esco products are sold to more than 100 countries through more than 300 independent distribution partners. Esco's biosafety cabinets are a world leader, providing a wide range of products in the industry and instrument installation at several institutes around the world.

Esco Lifesciences Group (hereinafter referred to as "Yisco Biological") provides supportive technologies, products and services to the life sciences and healthcare industries, supporting academic and scientific research, clinical practice, and the research and development and manufacturing of biopharmaceuticals. Yishike Biotech is headquartered in Singapore, with products and services covering more than 130 countries around the world. It has sales and service branches in more than 20 countries. It has 8 production and service branches in the United States, Europe, the United Kingdom, China, Singapore and Indonesia. R&D center has more than 1,700 employees worldwide.

Today, Yishike Biotech has entered the 3.0 era - using Singapore as the link between the East and the West, and based on a unique transnational strategy, it has established a global life science ecosystem. In May 2021, Yishike Bio completed a US$200 million Series A financing led by Vivo Capital and Novo Holdings A/S and followed by EDBI, and also participated in the follow-up support of internationally renowned investors such as China Investment Co., Ltd.

Yishike Bio's current business segments include Esco Scientific (hereinafter referred to as "Yishke Life Sciences"), Esco Medical (hereinafter referred to as "Yishke Medical") and Esco Healthcare (hereinafter referred to as "Yishke Pharmaceutical Machinery"). Yishike Life Sciences is a life science tool manufacturer dedicated to providing innovative solutions for clinical, scientific research and industrial fields; Yishike Medical, as a supplier of assisted reproductive technologies and solutions, opens business in three major regions around the world; Yishike Pharmaceutical Focusing on providing high-quality and customized solutions to support healthcare companies’ research and transformation processes, the tools needed for products from laboratory benches to clinical practice – whether in clinical trials, commercial production or drug formulation.

In 2020, Yishike Biotech's Jiangsu Taicang Production Center, which has invested more than 20,000 square meters in China, was officially put into production and used, actively responding to the "Healthy China" strategy. In 2021, Yishike Biotech actively promoted the process of localization of R&D, officially established Shanghai Zhangjiang R&D Center and Shenzhen R&D Center, and continued to increase investment in China and deepen its efforts in the Chinese market. In 2022, Yishike Biotechnology set up production plants in Suzhou, Jiangsu and Taicang, Jiangsu respectively. In the same year, Shanghai Yishike Pharmaceutical Technology Co., Ltd. was officially established to support the business development of Yishike Pharmaceutical Machinery Division in China.

Yishike Biotech actively responded to the "import substitution" policy. Now, all the business departments of Yishike Biotech have basically completed their production layout in China, including Taicang Yisgao Medical Equipment Technology Co., Ltd., Yishike (Suzhou) Precision Manufacturing Co., Ltd. Yishike (Jiangsu) Life Science Technology Co., Ltd. and Shanghai Yishike Pharmaceutical Technology Co., Ltd. Taicang Yisgao Medical Device Technology Co., Ltd. is mainly responsible for the production and manufacturing of life science equipment and medical equipment, providing support for Yishike Life Science and Yishike Medical Division; Yishike (Suzhou) Precision Manufacturing Co., Ltd. is mainly responsible for the production of equipment The precision processing of upstream raw materials required deeply supports the group's vertical integrated development; Yishike (Jiangsu) Life Science Technology Co., Ltd. is rooted in the field of biopharmaceuticals, with internationally leading product research and development capabilities and GMP-Like commercial Serving cutting-edge biological enterprises including antibody drugs, new crown vaccines, cell therapy and gene therapy; Shanghai Yishike Pharmaceutical Technology Co., Ltd. focuses on the customized development and manufacturing of special pharmaceutical isolators, ensuring the protection of Yishike Pharmaceutical Machinery Division Business is carried out in an orderly manner.