
BIOMIN

BIOMIN
Shanghai Beianji Biotechnology Co., Ltd. was established in December 2014 by Professor Tan Wensong's team of East China University of Science and Technology. It focuses on large-scale high-density serum-free suspension culture technology services and raw material development and manufacturing, providing biopharmaceutical companies with cells from the majority of cells. High-quality one-stop service from culture process development and optimization, medium formulation design to medium processing and manufacturing. The company's headquarters and R&D center are located in Zhangjiang Pharmaceutical Valley, Shanghai, and the Phase II production base (Shanghai Beijin Biotechnology Co., Ltd.) is located in Jinshan, Shanghai.
Since its establishment in 2014, Beanji has grown very rapidly and has independently developed nearly 100 catalog-type serum-free culture media for different cells, including Eden series CHO cell serum-free culture media for antibody protein expression, for cell therapy. The HIPP series of immune effector cells have serum-free culture medium, which is used for vaccine production such as Vero, HEK293, MDCK, PK15, BHK, MDBK, insect cells, etc. The product can support high-density culture and efficient amplification of cells, and its effect is better than other well-known culture medium products. It is easier to purify and downstream processing, effectively improving the safety and yield of cell products, and greatly reducing production costs for customers. The product quality and technical service level have surpassed imported similar products and are highly praised by domestic biopharmaceutical companies.
To date, Beanji supports more than 80 clinical application projects in the biopharmaceutical industry such as antibodies, vaccines, and cell/gene therapy, providing nearly 100 cell culture technology services, and has many domestic and international breakthrough project results. In the field of antibodies, Beanji helps customers to launch the first domestic antibody fusion protein drug that uses domestic medium formulas and processes. In the field of vaccines, the human/abvian influenza vaccine production based on MDCK cell serum-free suspension culture technology and the human vaccine (Phase III clinical) project based on VERO cell serum-free culture technology have been completed. In the field of cell therapy, the HIPP-T009 series of immune effector cell culture media independently developed by Beanji has become a real serum-free medium for high-density culture and maintenance of CAR-T cells and NK cells released in China, and is also used in China. Domestic culture medium that has been applied for clinical trials of cell therapy and has passed the CDE review.
By the end of 2021, the Beanji Phase II culture medium production base (Shanghai Beijin Biotechnology Co., Ltd.) will be fully put into production. The base is a world-class factory built in accordance with the requirements of ISO13485:2016 quality management system, GMP and MDSAP multi-system, and adopts LSS Lean 6 Sigma system for production management. It has achieved a thousand upgrades, tens of thousands of upgrades, and tens of thousands of upgrades to low-temperature needle mill powder technology. Consistent amplification, the maximum batch volume can reach 100,000 liters, with an annual production capacity of 55 million liters of powder culture medium and 250,000 liters of liquid culture medium. Beanji's products meet the requirements for culture medium by relevant regulations such as US FDA certification and EU product registration declaration.
Beanji is committed to supporting the research and development and production of innovative biological drugs such as antibodies, vaccines, cell therapy, etc. with stable and reliable high-quality culture medium products and services, and benefiting human health.
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